Description |
Most malaria cases do not result in death. However, virtually
all children habiting intense transmission areas suffer multiple and
repeated infections in their early years. Before the availability of
modern medical care, an estimated 20% of children in highly malarious
regions perished due to P.falciparum infections before they reached a
reproductive age. This mortality may have put great selective pressure on
the human genome with respect to drug resistance, immune evasion,and
disease virulence.
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