ASET Colloquium

"No-touch" physical methods to study cell behaviour dynamics

by Dr. Uma Ladiwala (Assistant Professor, UM-DAE Centre for Excellence in Basic Sciences)

Friday, September 6, 2013 from to (Asia/Kolkata)
at Colaba Campus ( AG-66 )
Description
The study of living single cells or cell-cell interactions in real time requires special techniques that can manipulate cells without involving any physical impingement or toxic chemicals. Optical trapping (tweezing), one such technique involving a laser-based approach, was used in conjunction with fluid flow technology to dissect the mechanics and spatio-temporal dynamics of how neural progenitor/stem cells (NSCs) adhere and aggregate in real time. The implications for neursophere formation and the neurosphere assay are discussed.

Another laser-based approach that can be applied to directional control of cell growth is the use of laser-patterned surfaces that enhance “wettability”. A brief description of some experiments and the usefulness of directed cell growth are “touched upon”.



Organised by Dr. Satyanarayana Bheesette