Description |
Over years transition metal catalyzed C−H activation has propelled the field of organic synthesis for the construction of structurally complex and diverse molecules. In this context, non-directed C−H activation has gained unprecedented attention for attaining region-specific C−H functionalizations in a step-economic mode. However, all existing non-directed C−H functionalizations utilize high thermal energy and super stoichiometric costly silver and copper salts to induce the functional group which eventually put the regioselectivity at stake. In aid of developing a more sustainable and environmentally benign approach, we have established a photoredox catalytic system by a merger of palladium/organo-photocatalyst(PC) which forges highly regeiospecific C−H olefination of diverse arenes and heteroarenes.
References:
Saha, A.;† Guin, S.;† Ali, W.; Bhattacharya, T.; Sasmal, S.; Goswami, N.; Prakash, G.; Sinha, S. K.; Chandrashekar, H. B.; Panda, S.; Anjana, S. S.; Maiti, D. J. Am. Chem. Soc. 2022, 144, 1929−1940
Dutta, U.; Maiti, S.; Bhattacharya, T.; Maiti, D. Science, 2021, 372, 701
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