Event calendar file
22-23 April 2024
TIFR
Asia/Kolkata timezone
- pellinac@gmail.com
Support
Production of 52Mn via natCr (p, n) 52Mn reaction and its radiochemical separation for preparation of radiopharmaceuticals
Presented by Dr. Rubel CHAKRAVARTY
on
23 Apr 2024
from
10:45 AM
to
11:00 AM
PI info
Dr. Rubel Chakravarty
local collaborator info
Shri S.C. Sharma, NPD, BARC
Collaborators Name
Shri S.C. Sharma, NPD, BARC
Motivation
Manganese-52 (T½ =5.6 d, Eβ+max = 575 keV; average Eβ+ = 242 keV, branching ratio β+ = 29.4 %) is an emerging radiometal that holds tremendous potential in nuclear medicine. The radioisotope can be produced in a low-energy particle accelerator using natural Cr-metal target via 52Cr (p, n) 52Mn reaction. Production, radiochemical separation and purification are the vital steps towards obtaining no-carrier-added (NCA) grade 52Mn in a form suitable for formulation of radiopharmaceuticals for cancer imaging.
Beam time requirement in shifts
12
Beam
Proton
Beam Energy
16 MeV
Beam Current
100-200
Beam Port
6M
Buncher Required
No
Target / Sample Details
Chromium metal powder
Whether the experiment is part of PhD work ?
No
Whether the experiment is part of Post-Doc work ?
No
information on the past beamtime at PLF
In the recent past, proton beam time was availed for production of 69Ge and 44Sc for formulation of PET radiopharmaceuticals.
Publication information related to prior work at the PLF
[1] Intrinsically 69Ge-Labeled Gum Arabic Glycoprotein Coated Gallium Oxide Nanoparticles: A New Nanoprobe for PET Imaging
Sanchita Ghosh, Sourav Patra, Apurav Guleria, Annu Balhara, Santosh Kumar Gupta, Avik Chakraborty, Sutapa Rakshit, Sanjay Vishwanath Thakare, Anil Krishna Debnath, Sudipta Chakraborty, Rubel Chakravarty*, Ind. Eng. Chem. Res. 2023, 62, 47, 20269–20279.
[2] Accelerator Production, Radiochemical Separation and Nanoradiopharmaceutical Formulation using 69Ge: A Next Generation PET Probe
Sourav Patra, Sanchita Ghosh, Khajan Singh, Bijaideep Dutta, Avik Chakraborty, Naresh Gamre, S. V. Thakare, K. C. Barick, Sutapa Rakshit, P. A. Hassan, Sudipta Chakraborty, Rubel Chakravarty*
J Drug Del Sci Technol 2024; 91: 105204.
Place
Location: TIFR
Room: AG66
