Chemical Sciences Seminars

Charge Transfer through Self-Assembled Monolayer of Peptide Nucleic Acid (PNA)

by Dr. Amit Paul (University of North Carolina at Chapel Hill)

Tuesday, June 28, 2011 from to (Asia/Kolkata)
at Colaba Campus ( AG-69 )
TIFR, Colaba, Mumbai 400005
Description

Charge transfer studies were performed for self-assembled monolayers of single-stranded and double-stranded peptide nucleic acids (PNAs) having a C-terminus cysteine and an N-terminus ferrocene group as a redox reporter. Charge transfer mechanism for short chain single-stranded PNA molecules was found to be superexchange mediated tunneling mechanism, whereas for long chain single-stranded and double-stranded PNAs, mechanism was multistep “hopping” mechanism. Also charge transfer rate of PNA molecules was found to be dependent on the oxidation potential of nucleobases. Excellent correlation between experimental charge transfer rate and theoretical conductance was observed.