Wednesday Colloquia

Photoinduced Regioselective Olefination of Arenes at Proximal and Distal Sites

by Prof. Debabrata Maiti (IIT Bombay, India)

Wednesday, December 7, 2022 from to (Asia/Kolkata)
at AG-66 and via ZOOM webinar ( Zoom link: https://zoom.us/j/97963259354?pwd=ZFZsa2xqWGJSZW5pUjZPNkNqeGlEZz09 )
Meeting ID: 979 6325 9354 Pass code: 04072020
Description
Over years transition metal catalyzed C−H activation has propelled the field of organic synthesis for the construction of structurally complex and diverse molecules. In this context, non-directed C−H activation has gained unprecedented attention for attaining region-specific C−H functionalizations in a step-economic mode.  However, all existing non-directed C−H functionalizations utilize high thermal energy and super stoichiometric costly silver and copper salts to induce the functional group which eventually put the regioselectivity at stake. In aid of developing a more sustainable and environmentally benign approach, we have established a photoredox catalytic system by a merger of palladium/organo-photocatalyst(PC) which forges highly regeiospecific C−H olefination of diverse arenes and heteroarenes. 

References:

Saha, A.;† Guin, S.;† Ali, W.; Bhattacharya, T.; Sasmal, S.; Goswami, N.; Prakash, G.; Sinha, S. K.; Chandrashekar, H. B.; Panda, S.; Anjana, S. S.; Maiti, D. J. Am. Chem. Soc. 2022, 144, 1929−1940    
  
Dutta, U.; Maiti, S.; Bhattacharya, T.; Maiti, D. Science, 2021, 372, 701