Metabolism and Aging: Exploring mechanisms that display emergent properties and ordered chaos

Biological mechanisms oscillate are different amplitudes and frequencies, which cumulatively dictate phenotypes manifested across scales from cells to tissues and organisms. More importantly, ability to respond to stimuli are governed by factors that encode plasticity and memory within the systems. This becomes even more intriguing in the context of physiological responses that span life-spans and generations. 

Gene-expression, metabolic changes and mitochondrial energetics have been considered to be one of the most dynamic, noisy and oscillatory parameters, which in addition to interacting with each other also produce several logic gates. Our efforts have discovered several such factors/pathways which drive the emergence of diseases and accelerated aging.

In this talk, I will provide an overview and explore the possibility of incorporating theoretical approaches to address one of the most complex biological phenomena. I would like to specifically discuss concepts like ordered chaos, interactions between multiple noisy oscillations and butterfly effects.

This talk will also be aimed at initiating a possible structured platform to enable interactions between biologists and theory colleagues across